Chelsea Handler has the hots for Robert De Niro.

“I’m very sexually attracted to Robert De Niro. I’m not gonna pretend that I’m not,” Chelsea Handler told Jimmy Fallon on Tuesday.

The comedian, 49, and De Niro, 80, both appeared on Tuesday’s episode of “The Tonight Show Starring Jimmy Fallon,” which reignited Handler’s love for the “Meet the Parents” actor.

Chelsea Handler appears on “The Tonight Show Starring Jimmy Fallon” on May 14.

“I couldn’t even go near him backstage, because his girlfriend’s back there, and I don’t want her to think that I’m making a move — but I want to make a move,” Handler said.

De Niro is dating Tiffany Chen, 45, and they have a 1-year-old daughter named Gia Virginia Chen-De Niro. Gia is De Niro’s seventh child.

Robert De Niro on the set of the “Zero Day” limited series in NYC on May 8, 2024.

“I have a penchant for elderly men,” Handler further explained to Fallon. “I always date older. At some point I’ll have to stop, you know, because it’s going to get too old. But I feel sexually attracted to Robert De Niro. I always have. And I would like to be penetrated by him.”

The audience laughed over Handler’s frank remarks as Fallon, who was also amused by her antics, tried to move on to a new topic.

Chelsea Handler reveals she has the hots for Robert De Niro to Jimmy Fallon.

Chelsea Handler tells Jimmy Fallon that she wants to “make a move” on Robert De Niro.

“I’m gonna change the subject,” he said with a laugh, before asking Handler about her new puppy and comedy tour.

De Niro did his own interview with Fallon that seemingly taped before Handler’s appearance, so Fallon couldn’t ask him about Handler’s comments.

Robert De Niro and Bobby Cannavale in a scene from their movie “Ezra.”

Handler appears to be single at the moment. Her last public relationship was with fellow comedian Jo Koy.

The exes had known each other for nearly 20 years before they started dating in the summer of 2021.

Koy, 52, frequently appeared as a guest on Handler’s E! late-night show “Chelsea Lately,” which ran from 2007 to 2014.

Chelsea Handler at “The Roast of Tom Brady” on May 5, 2024.

“One day, I just looked at him and I thought, ‘Oh, that’s my guy!’ ” Handler told Fallon in October 2021. “So, he’s like my best buddy, and then I also, you know, get to have sex with him … Fun time!”

Handler announced their split in July 2022, writing in a statement to fans, “It is with a heavy heart to announce that we have decided together that it is best for us to take a break from our relationship right now.”

Chelsea Handler outside CBS Studio in NYC on May 14, 2024.

“I know many of you were invested in our love, and I wanted to express to you how much that meant to both of us. How much it still means. And how much I now believe in love for each of us,” she added.